American Association of Feline Practitioners

Veterinary professionals passionate about the care of cats

Consensus Guidelines on the Long-term Use of NSAIDs in Cats

2024 ISFM/AAFP Consensus Guidelines on the Long-term Use of NSAIDs in Cats

Download - 2024 Consensus Guidelines on the Long-term Use of NSAIDs in Cats
Download - Client Brochure

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Veterinarians around the globe now have access to the latest Consensus Guidelines created by a panel of world-leading feline experts on the long-term use of non-steroidal anti-inflammatory drugs (NSAIDs) in cats. The most widely used analgesic in veterinary medicine, the 2024 ISFM and AAFP Consensus Guidelines on the Long-term Use of NSAIDs in Cats from the International Society of Feline Medicine (ISFM) and the American Association of Feline Practitioners (AAFP) supports practitioners with decision-making around prescribing NSAIDs in situations of chronic pain to minimize adverse effects and optimize pain management for their feline patients.

An extensive and practical guide to all aspects of the long-term use of NSAIDs in feline medicine, the Consensus Guidelines provide valuable resources for veterinarians and cover essential information including:

  • Mechanism of action of NSAIDs
  • Indications for their long-term use in cats
  • Assessing patient suitability and screening prior to prescription of NSAIDs
  • Considerations for NSAID use in the presence of comorbidities
  • Monitoring treatment efficacy
  • Avoidance and management of adverse effects
  • Considerations for anesthesia and surgery in cats receiving long-term NSAID therapy
  • Cat Friendly techniques to reduce chronic pain in the clinic and at home

The Consensus Guidelines also focus on providing Cat Friendly advice and tips for supporting caregivers to help improve compliance and therapeutic outcomes, while positively impacting the cat-caregiver bond. Three new guides for cat caregivers have been created by ISFM on supporting topics: Treating Chronic (Long-lasting) Pain with NSAIDs, Changes to the Home Environment for Cats with Muscle/Joint Pain or Mobility Problems, and Encouraging Your Cat to Drink, as well as a Treating Chronic Pain with NSAIDs Client Brochure from the AAFP to accompany the Consensus Guidelines.

Commenting on the evolution of the Consensus Guidelines, Sam Taylor, Head of Veterinary Specialists at ISFM and contributing author, said: “The first NSAID Guidelines were published in 2010. Since then, multiple studies have examined the use of NSAIDs in cats, particularly those with comorbidities. These Guidelines have examined this evidence and aim to provide practitioners with practical information on using NSAIDs for chronic pain management, along with tips and advice on working with caregivers to provide the best care for their cat.”

"We are thrilled to announce the release of these new Guidelines addressing long-term use of NSAIDs in cats,” added Heather O’Steen, AAFP CEO. “With a focus on safety, efficacy, and responsible medication management, these Guidelines aim to enhance the quality of life for cats while minimizing potential risks. We believe that these Guidelines will serve as a vital resource in ensuring the optimal care and wellbeing of cats receiving long-term NSAID therapy."

The Task Force includes Samantha Taylor, BVetMed (Hons), CertSAM, DipECVIM-CA, MANZCVS, FRCVS (Chair); Margaret Gruen, DVM, MVPH, PhD, DACVB; Kate KuKanich, DVM, PhD, DipACVIM (SAIM); B Duncan X Lascelles, BVSc, BSc, CertVA, PhD, DipECVS, DSAS(Soft Tissue), DipACVS, FRCVS; Beatriz P Monteiro, DVM, PhD, ISFMAdvCertFB, PgDip; Sheilah Robertson, BVMS (Hons), CertVA, PhD, DACVAA, DECVAA, DACAW, DECAWBM (AWSEL), FRCVS; Llibertat Real Sampietro, DVM, Acre AVEPA in Feline Medicine; and Paulo V Steagall, MV, MS, PhD, DipACVAA.



*This Guideline updates and replaces the 2010 AAFP/ISFM Long Term Use of NSAIDS in Cats.